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Effect of high-fat diets on body composition, lipid metabolism and insulin sensitivity, and the role of exercise on these parameters BJMBR
Coelho,D.F.; Pereira-Lancha,L.O.; Chaves,D.S.; Diwan,D.; Ferraz,R.; Campos-Ferraz,P.L.; Poortmans,J.R.; Lancha Junior,A.H..
Dietary fat composition can interfere in the development of obesity due to the specific roles of some fatty acids that have different metabolic activities, which can alter both fat oxidation and deposition rates, resulting in changes in body weight and/or composition. High-fat diets in general are associated with hyperphagia, but the type of dietary fat seems to be more important since saturated fats are linked to a positive fat balance and omental adipose tissue accumulation when compared to other types of fat, while polyunsaturated fats, omega-3 and omega-6, seem to increase energy expenditure and decrease energy intake by specific mechanisms involving hormone-sensitive lipase, activation of peroxisome proliferator-activated receptor α (PPARα) and...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Fat; Obesity; Insulin; PUFA; Diet; Exercise.
Ano: 2011 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2011001000001
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Swimming training down-regulates plasma leptin levels, but not adipose tissue ob mRNA expression BJMBR
Benatti,F.B.; Polacow,V.O.; Ribeiro,S.M.L.; Gualano,B.; Coelho,D.F.; Rogeri,P.S.; Costa,A.S.; Lancha Junior,A.H..
The aim of the present study was to assess the effects of endurance training on leptin levels and adipose tissue gene expression and their association with insulin, body composition and energy intake. Male Wistar rats were randomly divided into two groups: trained (N = 18) and sedentary controls (N = 20). The trained group underwent swimming training for 9 weeks. Leptin and insulin levels, adiposity and leptin gene expression in epididymal and inguinal adipose tissue were determined after training. There were no differences in energy intake between groups. Trained rats had a decreased final body weight (-10%), relative and total body fat (-36 and -55%, respectively) and insulin levels (-55%) compared with controls (P < 0.05). Although trained animals...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Swimming training; Leptin mRNA; Body weight; Adipose tissue; Insulin levels; Rats.
Ano: 2008 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2008001000006
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